Cytokine profile in fatal human immunodeficiency virus tuberculosis Epstein-Barr virus associated hemophagocytic syndrome.

Correspondence: Dr Myles, Division of Retrovirology, Walter Reed Army Institute of Research, 1 Taft Ct, Ste 250, Rockville, MD 20850 ([email protected]). Author Contributions: Study concept and design: Myles, Wortmann, Cummings, and Gasser. Acquisition of data: Myles, Wortmann, Cummings, Barthel, Patel, CrumCianflone, Negin, Weina, Ockenhouse, Joyce, Magill, Aronson, and Gasser. Analysis and interpretation of data: Myles, Wortmann, Cummings, Barthel, CrumCianflone, Weina, Magill, Aronson, and Gasser. Drafting of the manuscript: Myles, Wortmann, Patel, Magill, and Gasser. Critical revision of the manuscript for important intellectual content: Myles, Wortmann, Cummings, Barthel, Crum-Cianflone, Negin, Weina, Ockenhouse, Joyce, Magill, Aronson, and Gasser. Administrative, technical, and material support: Myles, Cummings, Patel, Negin, Weina, Ockenhouse, and Aronson. Study supervision: Myles, Wortmann, Crum-Cianflone, Magill, and Gasser. Financial Disclosure: None reported. Disclaimer: Theopinionorassertionscontainedhereinare the private views of the authors and are not to be construed as official or as reflecting the views of the Departments of the Army, of the Navy or of Defense. Additional Contributions: We thank all of the individuals involved at the various institutions providing clinical care and diagnostic services for these patients, especially the nursing staff in the infectious disease clinic and medicine ward at Walter Reed Army Medical Center; the diagnostic laboratory staff at the Walter Reed Army Institute of Research and the Armed Forces Institute of Pathology (Ron Neafie, MS, and Peter McEvoy, MD); Barbara Herwaldt, MD, MPH, at the CDC; and the physicians at Landstuhl Army Medical Center, Germany (Fareed Sheikh, MD, Donald Edelheit, MD, James Hu, MD, and Donald Taillon, MD).